Vaccination is most effective way to control HIV/AIDS but it would take another decade or more for a suitable vaccine candidate to reach to the market. Till then only available single drug or multiple drug therapy has to play important role. Still issues like large dose, poor patient adherence and efficacy, high toxicity etc. after orally administration of antiretrovirals remain as it is and can only be taken care by intelligent nanoparticle design. Research done until now shows that nanoparticles have potential to reduce dosing frequency, toxicity and can target particular organ or cells and eradicate viral reservoirs if administered parenterally which is debated all the time.
Drug targeting of antiretroviral using nanoparticles
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