Nanotechnology is being widely studied in bone repair or regeneration treatments in the form of scaffolds because of improved efficacy and selective targeting in comparison to conventional approaches. Nanoparticle-based drug delivery is a choice in many conditions, such as bone infections, cancer bone metastasis, osteosarcoma, inflammatory diseases, and many other conditions like osteoarthritis and bone […]

Advancement in cancer research and therapies is fastened by possibilities of record-breaking technologies and its applications. Lot of limitations like drug properties, industrial scale up and stability and clinical still hinder the path of drug candidates to clinical trial. However, collaboration of clinicians with research scientist, chemist, and academia is adding value to the new […]

Liposomes, polymeric, lipid and inorganic nanoparticles have dominated and proved their clinical effectiveness as a therapeutic or diagnostic agent in oncology research. Being new in concept, PLH nanoparticles witnessed superior performance due to the smart engineering of lipid and polyer counter part by overcoming the limitations of well-established nanocarriers. Notably, PLH nanostructures offered a versatile […]

Positively charged CUR-PLGA-NPs increased depth of tissue penetration by 81.5% and tissue concentration by 80%. Electrostatic precipitation further improved the uptake of positively charged CUR-PLGA-NPs by 41.8%. The combination of positive charge and electrostatic precipitation have significant potential to improve tissue uptake of nanoparticles during intraperitoneal chemotherapy. https://doi.org/10.2217/nnm-2020-0373