Zeta potential of positively charged lipid nanoparticle.

Dermal targeting and protective mechanism by application of lipid nanoparticle.

Organ targeting of nanocrystals depicted by Gamma scintigraphy. Transmission electron microscopy clearly indicates penetration of drug loaded polymeric nanoparticles inside the tissue.

A positron emission tomography (PET) scan is an imaging test that can help reveal the metabolic or biochemical function of your tissues and organs. PET imagining of lipid nanoparticles upon IV administration.

The basics first- The high costs of drug development (for both successful and unsuccessful candidates) results in exorbitant drug prices, leading to high healthcare expenditure. The only solution to reduce this burden is open communication between all science streams involved during the complete cycle, better alignment on “regulatory requirement” and “right experimental design,” along with […]

Vaccination is most effective way to control HIV/AIDS but it would take another decade or more for a suitable vaccine candidate to reach to the market. Till then only available single drug or multiple drug therapy has to play important role. Still issues like large dose, poor patient adherence and efficacy, high toxicity etc. after […]

Icodextrin (IDX) is an antiadhesive polymer that can be used as a carrier solution for intraperitoneal (IP) delivery of chemotherapeutic drugs. We examined the sprayability of IDX, the aerosol characteristics, the stability of the molecule after aerosolization, the effects of IDX on the adhesion of MKN45 human gastric cancer cells, the synergistic effect of aerosolized […]

Marine bioproducts like algae have a lot of potential in food, cosmetic and nutraceutical industry. Formulation is key to all these markets. To extract the potential benefits of algae is very important especially the solubility issues of available sticky/powder extracts. Nanosuspension offers ease of production, simple formulation steps and enhanced formulation performance of nano algae […]

Surface hydrophobicity of nanocarriers influences protein binding and subsequently fate in blood circulation. Therefore, characterization of surface properties of nanocarriers provides important preclinical information. Rose Bengal adsorption method was developed as easy and quick method for surface hydrophobicity characterization and was successfully used for various types of nanocarriers. Here, we revised the method for the […]

The scientific community considers the lipid nanoparticles as very promising delivery system, as shown by the many research groups working meanwhile with SLN and NLC. Lipid nanoparticles already made it to the cosmetic market. This proves the makeability of products and of large scale production ability – both being important prerequisites for a pharmaceutical product. […]